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KMID : 1145520170030020122
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Journal of Radiopharmaceuticals and Molecular Probes
2017 Volume.3 No. 2 p.122 ~ p.128
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Transition metal-mediated/catalyzed fluorination methodology developed in the 2000s
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Bae Dae-Young
Lee Eun-Sung
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Abstract
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In the 2000s, there has been a significant advance on carbon?fluorine (C?F) bond formation reactions via transition metal mediated or catalyzed methods. Of course, for the past 10 years, transition metal catalysis improves C-F bond formation in terms of practicality and even can be applied to C-18F bond formation reaction. In this mini-review, we summarize various transition metal mediated or catalyzed fluorination reactions, which were developed in the mid-2000s.
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KEYWORD
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Fluorination, Carbon?fluorine, Transition metals, Catalysis
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